Indication
Treatment or prevention of, Vitamin C Deficiency, Scurvy, Infection, Trauma, Burns, Cold exposure, Following Surgery, common cold, Fever, scurvy, Stress, Cancer, Methemoglobinemia and Children receiving unfortified formulas. Also indicated in, Hematuria, Dental Caries, Gum Diseases, Pyorrhea, Acne, Infertility, Atherosclerosis, Fractures, Leg ulcers, Hay fever, Vascular thrombosis prevention, Levodopa toxicity, Arsenic toxicity.

Administration
May be taken with or without food. IV Preparation Dilute with large volume of compatible fluid to minimize adverse reactions Compatible w/ most common diluents (dextrose solns, NS, LR, Ringer's, ½NS, dextrose-saline, dextrose-LR etc) IV Admin...
... Show more
Adult Dose
Oral Scurvy Adult: Prevention: 25-75 mg daily. 4 tablets 2 to 3 times daily. Treatment: >250 mg daily, given in divided doses. May also be given via IM/IV/SC admin. 250-500mg IV qDay/BID for at least 2 weeks. Thalassaemia Adult: 100-200 ...
... Show more
Child Dose
Children: Child: 1 mth-4 yr: 125-250 mg daily; 4-12 yr: 250-500 mg daily; 12-18 yr: 500 mg-1 g daily. Doses to be given in 1-2 divided doses. Thalassaemia Child: 100-200 mg daily, to be given with desferrioxamine. Metabolic disorders ...
... Show more
Mode of Action
Vitamin C: Necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic ...
... Show more
Precaution
Should be given with caution to patient with hyperoxaluria.
Side Effect
Flushing, Flank pain, Faintness, headache, Diarrhea, dyspepsia, nausea, vomiting, Hyperoxaluria (large doses)
Interaction
Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.